84%
of people were more likely to start or complete a task*
100%
75%
50%
25%
0%
★★★★☆
(8,062)
Neupril Pure Methylfolate
5-MTHF + B12 Complex
- Supports methylation & brain health
- Clears brain fog & reduces fatigue
- Boosts focus, clarity, & sustained energy
- Promotes balanced stress response
- Nourishes healthy skin & stronger hair
Active folate and B12
30-day guarantee
Choose Your Offer
Why Neupril? +
Neupril Pure Methylfolate gives you the active form of folate your body can readily use, especially when conversion issues are a concern.
Ingredients & Allergies +
A clean liquid formula with active 5-MTHF and methyl B12. Replace this copy with final supplement facts and allergy details.
Science & Certifications +
Made for bioavailability and third-party quality standards, with space here for final certifications.
Shipping & Returns +
Orders ship quickly and first-time customers can use the 30-day guarantee.
Directions +
Shake well and take daily as directed on your final product label.
Benefits +
Supports methylation, energy, focus, mood, and healthy brain function.
No Heavy Metals & Microbes
Non-GMO
No Artificial Ingredients
Vegan
Bioavailable Form
Third-Party Tested
No Heavy Metals & Microbes
Non-GMO
No Artificial Ingredients
Vegan
Bioavailable Form
Third-Party Tested
After 60 Days
Neupril has helped hundreds of thousands of customers focus—and follow through.
Don't just take our word for it. See for yourself what Neupril customers experience within 60 days of taking methylfolate + methyl B12.
Neupril results timeline
Lift the fog, feel the difference
Methylfolate supports neurotransmitter synthesis, helping clear brain fog and calm anxious thoughts.*
Real natural energy, not caffeine highs
Steady methylation support helps boost dopamine and serotonin for more focus, drive, and a balanced mood. Without the crash.*
Break the burnout cycle
Consistent use supports nervous system recovery and resilience, helping you stay clear-headed, motivated, and grounded even under stress or during recovery.*
Rebuild focus and emotional balance
Long-term use strengthens attention, mood stability, and motivation. Helping you feel more like yourself again.*
Clinically Backed Nutrients For Real, Noticeable Benefits
L-5-methyltetrahydrofolate (L-5-MTHF)
Key Function
Supports methylation and neurotransmitter production
Methylcobalamin (Methyl-B12)
Key Function
Supports energy production and neurological function
Benefits You Can See and Feel
Clean Energy
Gives your cells the raw material to convert food into sustained energy without the crash.
Deep Sleep
Supports restful sleep by promoting healthy serotonin and melatonin production naturally.
Mood Boost
Helps your body produce serotonin and dopamine naturally to support emotional balance and well-being.
DNA & Detox
Activates your body's master regulator for gene expression, cellular repair, and toxin clearance.
Sharp Focus
Sharpens mental clarity and concentration by supporting the neurotransmitters your brain relies on.
Brain Health
Fuels the neurotransmitters your mind runs on for sharper thinking and lasting mental clarity.
Clean Energy
Gives your cells the raw material to convert food into sustained energy without the crash.
Deep Sleep
Supports restful sleep by promoting healthy serotonin and melatonin production naturally.
Mood Boost
Helps your body produce serotonin and dopamine naturally to support emotional balance and well-being.
DNA & Detox
Activates your body's master regulator for gene expression, cellular repair, and toxin clearance.
Sharp Focus
Sharpens mental clarity and concentration by supporting the neurotransmitters your brain relies on.
Brain Health
Fuels the neurotransmitters your mind runs on for sharper thinking and lasting mental clarity.
Us vs. Them
Not overhyped or overpriced. Just pure methylfolate + methyl B12 made enjoyable and for every unique brain.
Neupril
Others
Clinical Strength
⇩
Fast Absorption
⇩
Clean Ingredients
⇩
Methyl B12 Cofactor
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Delicious Taste
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Tested, Trusted, and Certified
Neupril’s methylfolate is third-party tested to confirm purity, potency, and safety, ensuring every drop meets clinical standards and is free from heavy metals, microbes, and unwanted fillers.
Gluten Free
USA Made
Clinical Studies
Quality Verified
Any last questions?
Try NeuprilMost customers notice clearer focus, steadier energy, or improved mood within the first few weeks of daily use. Results vary based on your body, diet, and how consistently you take Neupril.
Neupril is designed for daily use when taken as directed on the label. If you are pregnant, nursing, taking medication, or managing a health condition, talk with your healthcare provider first.
Many people take methylfolate alongside other supplements, but combinations can matter—especially with prescription medications. Always confirm with your doctor or pharmacist before adding Neupril to your routine.
Follow the serving size on your product label unless your healthcare provider recommends otherwise. Body weight alone usually does not require a different dose for most adults.
You do not need a confirmed MTHFR diagnosis to benefit from active methylfolate. Neupril provides the bioactive form your body can use directly, which is helpful when standard folic acid conversion is inefficient.
Neupril has a mild, easy-to-take liquid format that most customers describe as light and simple to swallow on its own or mixed into a small amount of water or juice.
Customer reviews
4.26
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8,058 reviews
Jacob C.
Verified buyer
Never felt more natural energy after a week. I take it every morning and my afternoons feel smoother with less crash and more focus.
Ruth H.
Verified buyer
Works better with daily consistency. Once I stayed on it for two weeks, the brain fog lift was obvious and the liquid format is easy.
Rebecca L.
Verified buyer
Good quality and easy to take. The dropper makes dosing simple and I like that it uses active methylfolate.
Kelly S.
Verified buyer
Helped my mood and focus together. I have tried other folate products before and Neupril feels cleaner when I stay consistent.
Would recommend
Amber M.
Verified buyer
Finally something my body seems to use. Regular folic acid never did much for me, but Neupril made my mornings much more productive.
Tina N.
Verified buyer
Great for busy moms. One minute, done. Energy feels steadier and I am less irritable by dinner time.
Would recommend
Dana P.
Verified buyer
Solid supplement with subtle but real results. After three weeks my focus at work improved and I stopped reaching for extra coffee.
Miley S.
Verified buyer
I love how easy Neupril is to take and how good I feel every day. Customer service was amazing too.
Chris G.
Verified buyer
More calm and focused after years of struggling with folate conversion. This active form made a noticeable difference.
Would recommend
Kylie L.
Verified buyer
Brain fog is mostly gone. Energy is up, thinking feels clearer, and the afternoon slump is much lighter now.
Jordan R.
Verified buyer
Worth staying consistent. First week was mild, second week better, third week I really noticed improved follow-through.
Renee T.
Verified buyer
Best methylfolate I have tried. Neupril is the first where I felt a clear difference in energy and mental clarity.
Would recommend
Hannah B.
Verified buyer
Simple routine, real results. The liquid format is easy and I feel more even emotionally and less fatigued.
Laura W.
Verified buyer
Good experience overall. Shipping was fast and I noticed better focus during long work sessions.
Nina F.
Verified buyer
Helps me stay on track. I am more consistent with my habits and less overwhelmed since starting Neupril daily.
Would recommend
Eva V.
Verified buyer
Noticeable in two weeks. I feel more alert in meetings and less mentally tired by evening.
Sarah O.
Verified buyer
Great for methylation support. My functional medicine provider recommended active folate and this is easy to stick with.
Paula M.
Verified buyer
Steady improvement rather than overnight change, but mood and energy kept building over a month.
Allison L.
Verified buyer
Highly recommend. Easy to take, no weird aftertaste, and I genuinely feel better day to day.
Would recommend
Brooke T.
Verified buyer
Clearer mind and better energy. The combination of methylfolate and B12 feels balanced without feeling wired.
Julie M.
Verified buyer
Part of my daily wellness stack now. Focus and mood both improved within the first month.
Would recommend
Danielle W.
Verified buyer
Quality product with clear instructions. I appreciate the third-party testing transparency.
Reviewed on Junip